Advanced production and digital technologies are offering new opportunities for more responsive, flexible and distributed manufacturing. E-Commerce models are also emerging, as are digital platform businesses, that are connecting end-users with producers and service providers. Whilst these technology developments suggest radically different digitalised manufacturing supply chains, technology adoption is far from straightforward, with many pilot applications not progressing to full scale. So is this transformation more hype than reality?  Our industry speakers were invited to address real-world applications that are making a difference in their organisations. Academic keynotes shared insights on how we might reconceptualise our supply chain operations and escape the pilot purgatory of experimentation without exploitation.